| Title | Cited by | Year |
|---|---|---|
| ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury
V Finck?Barbançon, J Goranson, L Zhu, T Sawa, JP Wiener?Kronish, …
Molecular microbiology 25 (3), 547-557
|
396 | 1997 |
| ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system
TL Yahr, AJ Vallis, MK Hancock, JT Barbieri, DW Frank
Proceedings of the National Academy of Sciences 95 (23), 13899-13904
|
388 | 1998 |
| Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections
A Roy-Burman, RH Savel, S Racine, BL Swanson, NS Revadigar, …
Journal of Infectious Diseases 183 (12), 1767-1774
|
387 | 2001 |
| The exoenzyme S regulon of Pseudomonas aeruginosa
DW Frank
Molecular microbiology 26 (4), 621-629
|
376 | 1997 |
| Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia
K Kurahashi, O Kajikawa, T Sawa, M Ohara, MA Gropper, DW Frank, …
The Journal of clinical investigation 104 (6), 743-750
|
316 | 1999 |
| Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury
T Sawa, TL Yahr, M Ohara, K Kurahashi, MA Gropper, JP Wiener-Kronish, …
Nature medicine 5 (4), 392-398
|
299 | 1999 |
| Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway
TL Yahr, J Goranson, DW Frank
Molecular microbiology 22 (5), 991-1003
|
292 | 1996 |
| The mechanism of action of the Pseudomonas aeruginosa?encoded type III cytotoxin, ExoU
H Sato, DW Frank, CJ Hillard, JB Feix, RR Pankhaniya, K Moriyama, …
The EMBO Journal 22 (12), 2959-2969
|
267 | 2003 |
| Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S.
SM Fleiszig, JP Wiener-Kronish, H Miyazaki, V Vallas, KE Mostov, …
Infection and immunity 65 (2), 579-586
|
261 | 1997 |
| Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon.
TL Yahr, LM Mende-Mueller, MB Friese, DW Frank
Journal of bacteriology 179 (22), 7165-7168
|
224 | 1997 |
| ExoU is a potent intracellular phospholipase
H Sato, DW Frank
Molecular microbiology 53 (5), 1279-1290
|
207 | 2004 |
| Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis
S Miyata, M Casey, DW Frank, FM Ausubel, E Drenkard
Infection and immunity 71 (5), 2404-2413
|
185 | 2003 |
| The amino?terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small?molecular?weight GTP?binding proteins
KJ Pederson, AJ Vallis, K Aktories, DW Frank, JT Barbieri
Molecular microbiology 32 (2), 393-401
|
148 | 1999 |
| Regulation of ExoS Production and Secretion byPseudomonas aeruginosa in Response to Tissue Culture Conditions
AJ Vallis, TL Yahr, JT Barbieri, DW Frank
Infection and immunity 67 (2), 914-920
|
146 | 1999 |
| Biological effects of Pseudomonas aeruginosa type III-secreted proteins on CHO cells
AJ Vallis, V Finck-Barbançon, TL Yahr, DW Frank
Infection and immunity 67 (4), 2040-2044
|
141 | 1999 |
| Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon.
AK Hovey, DW Frank
Journal of bacteriology 177 (15), 4427-4436
|
136 | 1995 |
| Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury
I Kudoh, JP Wiener-Kronish, S Hashimoto, JF Pittet, D Frank
American Journal of Physiology-Lung Cellular and Molecular Physiology 267 (5 …
|
133 | 1994 |
| Genetic relationship between the 53-and 49-kilodalton forms of exoenzyme S from Pseudomonas aeruginosa.
TL Yahr, JT Barbieri, DW Frank
Journal of bacteriology 178 (5), 1412-1419
|
129 | 1996 |
| Construction and characterization of a highly efficient Francisella shuttle plasmid
TM Maier, A Havig, M Casey, FE Nano, DW Frank, TC Zahrt
Applied and environmental microbiology 70 (12), 7511-7519
|
127 | 2004 |
| Pseudomonas aeruginosa exoenzyme S ADP-ribosylates Ras at multiple sites
AK Ganesan, DW Frank, RP Misra, G Schmidt, JT Barbieri
Journal of Biological Chemistry 273 (13), 7332-7337
|
123 | 1998 |
| Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing.
G Apodaca, M Bomsel, R Lindstedt, J Engel, D Frank, KE Mostov, …
Infection and immunity 63 (4), 1541-1551
|
120 | 1995 |
| Transcriptional analysis of the Pseudomonas aeruginosa exoenzyme S structural gene.
TL Yahr, AK Hovey, SM Kulich, DW Frank
Journal of bacteriology 177 (5), 1169-1178
|
119 | 1995 |
| Effect of Pseudomonas aeruginosa elastase, alkaline protease, and exotoxin A on corneal proteinases and proteins.
SS Twining, SE Kirschner, LA Mahnke, DW Frank
Investigative ophthalmology & visual science 34 (9), 2699-2712
|
119 | 1993 |
| Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV
DW Frank, A Vallis, JP Wiener-Kronish, A Roy-Burman, EG Spack, …
Journal of Infectious Diseases 186 (1), 64-73
|
118 | 2002 |
| Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits
JP Wiener-Kronish, T Sakuma, I Kudoh, JF Pittet, D Frank, L Dobbs, …
Journal of Applied Physiology 75 (4), 1661-1669
|
118 | 1993 |
| In Vitro Cellular Toxicity PredictsPseudomonas aeruginosa Virulence in Lung Infections
T Sawa, M Ohara, K Kurahashi, SS Twining, DW Frank, DB Doroques, …
Infection and immunity 66 (7), 3242-3249
|
117 | 1998 |
| Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme S synthesis in Pseudomonas aeruginosa.
DW Frank, BH Iglewski
Journal of bacteriology 173 (20), 6460-6468
|
114 | 1991 |
| ExoT of Cytotoxic Pseudomonas aeruginosaPrevents Uptake by Corneal Epithelial Cells
BA Cowell, DY Chen, DW Frank, AJ Vallis, SMJ Fleiszig
Infection and immunity 68 (1), 403-406
|
100 | 2000 |
| Cloning the structural gene for the 49-kDa form of exoenzyme S (exoS) from Pseudomonas aeruginosa strain 388.
SM Kulich, TL Yahr, LM Mende-Mueller, JT Barbieri, DW Frank
Journal of Biological Chemistry 269 (14), 10431-10437
|
97 | 1994 |
| Pseudomonas aeruginosa invasion and cytotoxicity are independent events, both of which involve protein tyrosine kinase activity
DJ Evans, DW Frank, V Finck-Barbançon, C Wu, SMJ Fleiszig
Infection and immunity 66 (4), 1453-1459
|
96 | 1998 |
| Construction and characterization of chromosomal insertional mutations of the Pseudomonas aeruginosa exoenzyme S trans-regulatory locus.
DW Frank, G Nair, HP Schweizer
Infection and immunity 62 (2), 554-563
|
96 | 1994 |
| Transcriptional organization of the trans-regulatory locus which controls exoenzyme S synthesis in Pseudomonas aeruginosa.
TL Yahr, DW Frank
Journal of bacteriology 176 (13), 3832-3838
|
86 | 1994 |
| Modification of Ras in eukaryotic cells by Pseudomonas aeruginosa exoenzyme S
EM McGuffie, DW Frank, TS Vincent, JC Olson
Infection and immunity 66 (6), 2607-2613
|
84 | 1998 |
| Paradoxical cAMP-induced lung endothelial hyperpermeability revealed by Pseudomonas aeruginosa ExoY
SL Sayner, DW Frank, J King, H Chen, J VandeWaa, T Stevens
Circulation research 95 (2), 196-203
|
83 | 2004 |
| Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A
MJ Wick, DW Frank, DG Storey, BH Iglewski
Annual Reviews in Microbiology 44 (1), 335-363
|
81 | 1990 |
| Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophages
TM Maier, MS Casey, RH Becker, CW Dorsey, EM Glass, N Maltsev, …
Infection and immunity 75 (11), 5376-5389
|
80 | 2007 |
| In vivo Himar1-based transposon mutagenesis of Francisella tularensis
TM Maier, R Pechous, M Casey, TC Zahrt, DW Frank
Applied and environmental microbiology 72 (3), 1878-1885
|
76 | 2006 |
| Role of exoenzyme S in chronicPseudomonas aeruginosa lung infections
TI Nicas, DW Frank, P Stenzel, JD Lile, BH Iglewski
European journal of clinical microbiology 4 (2), 175-179
|
75 | 1985 |
| Macrophages and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system
J Coburn, DW Frank
Infection and immunity 67 (6), 3151-3154
|
74 | 1999 |
| Effects of differential expression of the 49-kilodalton exoenzyme S by Pseudomonas aeruginosa on cultured eukaryotic cells.
JC Olson, EM McGuffie, DW Frank
Infection and immunity 65 (1), 248-256
|
72 | 1997 |
| Type III secretion/intoxication system important in virulence of Pseudomonasaeruginosa infections in burns
IA Holder, AN Neely, DW Frank
Burns 27 (2), 129-130
|
71 | 2001 |
| Differential regulation by iron of regA and toxA transcript accumulation in Pseudomonas aeruginosa.
DW Frank, DG Storey, MS Hindahl, BH Iglewski
Journal of bacteriology 171 (10), 5304-5313
|
71 | 1989 |
| Kinetics of toxA and regA mRNA accumulation in Pseudomonas aeruginosa.
DW Frank, BH Iglewski
Journal of bacteriology 170 (10), 4477-4483
|
71 | 1988 |
| Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strain
R Pechous, J Celli, R Penoske, SF Hayes, DW Frank, TC Zahrt
Infection and immunity 74 (8), 4452-4461
|
70 | 2006 |
| Type IV pili in Francisella tularensis: roles of pilF and pilT in fiber assembly, host cell adherence, and virulence
S Chakraborty, M Monfett, TM Maier, JL Benach, DW Frank, DG Thanassi
Infection and immunity 76 (7), 2852-2861
|
68 | 2008 |
| Identification and characterization of SpcU, a chaperone required for efficient secretion of the ExoU cytotoxin
V Finck-Barbançon, TL Yahr, DW Frank
Journal of bacteriology 180 (23), 6224-6231
|
67 | 1998 |
| Acquisition and evolution of the exoU locus in Pseudomonas aeruginosa
BR Kulasekara, HD Kulasekara, MC Wolfgang, L Stevens, DW Frank, …
Journal of bacteriology 188 (11), 4037-4050
|
66 | 2006 |
| PcrV immunization enhances survival of burned Pseudomonas aeruginosa-infected mice
IA Holder, AN Neely, DW Frank
Infection and immunity 69 (9), 5908-5910
|
64 | 2001 |
| Multiple domains are required for the toxic activity of Pseudomonas aeruginosa ExoU
V Finck-Barbançon, DW Frank
Journal of bacteriology 183 (14), 4330-4344
|
64 | 2001 |
| Biochemical relationships between the 53-kilodalton (Exo53) and 49-kilodalton (ExoS) forms of exoenzyme S of Pseudomonas aeruginosa.
S Liu, TL Yahr, DW Frank, JT Barbieri
Journal of bacteriology 179 (5), 1609-1613
|
60 | 1997 |
| Identification of superoxide dismutase as a cofactor for the pseudomonas type III toxin, ExoU
H Sato, JB Feix, DW Frank
Biochemistry 45 (34), 10368-10375
|
59 | 2006 |
| Interruption of Multiple Cellular Processes in HT-29 Epithelial Cells by Pseudomonas aeruginosaExoenzyme S
JC Olson, JE Fraylick, EM McGuffie, KM Dolan, TL Yahr, DW Frank, …
Infection and immunity 67 (6), 2847-2854
|
59 | 1999 |
| A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge
RD Pechous, TR McCarthy, NP Mohapatra, S Soni, RM Penoske, …
PLoS One 3 (6), e2487
|
58 | 2008 |
| Expression of recombinant exoenzyme S of Pseudomonas aeruginosa.
SM Kulich, DW Frank, JT Barbieri
Infection and immunity 63 (1), 1-8
|
57 | 1995 |
| Characterization of phospholipase activity of the Pseudomonas aeruginosa type III cytotoxin, ExoU
H Sato, JB Feix, CJ Hillard, DW Frank
Journal of bacteriology 187 (3), 1192-1195
|
54 | 2005 |
| Purification and characterization of exoenzyme S from Pseudomonas aeruginosa 388.
SM Kulich, DW Frank, JT Barbieri
Infection and immunity 61 (1), 307-313
|
54 | 1993 |
| Multiple promoters control the regulation of the Pseudomonas aeruginosa regA gene
DG Storey, DW Frank, MA Farinha, AM Kropinski, BH Iglewski
Molecular microbiology 4 (3), 499-503
|
52 | 1990 |
| Sera from adult patients with cystic fibrosis contain antibodies to Pseudomonas aeruginosa type III apparatus
J Moss, ME Ehrmantraut, BD Banwart, DW Frank, JT Barbieri
Infection and immunity 69 (2), 1185-1188
|
49 | 2001 |
| Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis
MA Apicella, DMB Post, AC Fowler, BD Jones, JA Rasmussen, JR Hunt, …
PLoS One 5 (7), e11060
|
48 | 2010 |
| Cytotoxic Strains of Pseudotnonas aeruginosa Can Damage the Intact Corneal Surface In Vitro.
SMJ Fleiszig, EJ Lee, C Wu, RC Andika, V Valias, M Portoles, DW Frank
Eye & Contact Lens 24 (1), 41-47
|
47 | 1998 |
| Interaction of monoclonal antibodies with pertussis toxin and its subunits.
DW Frank, CD Parker
Infection and immunity 46 (1), 195-201
|
42 | 1984 |
| Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa
MJ Wick, DW Frank, DG Storey, BH Iglewski
Molecular microbiology 4 (3), 489-497
|
41 | 1990 |
| Intracellular localization and processing of Pseudomonas aeruginosa ExoS in eukaryotic cells
KJ Pederson, S Pal, AJ Vallis, DW Frank, JT Barbieri
Molecular microbiology 37 (2), 287-299
|
39 | 2000 |
| Molecular studies of a positive regulator of toxin A synthesis in Pseudomonas aeruginosa
MS Hindahl, DW Frank, BH Iglewski
Karger Publishers
|
39 | 1987 |
| Pseudolipasin A is a specific inhibitor for phospholipase A2 activity of Pseudomonas aeruginosa cytotoxin ExoU
VT Lee, S Pukatzki, H Sato, E Kikawada, AA Kazimirova, J Huang, X Li, …
Infection and immunity 75 (3), 1089-1098
|
37 | 2007 |
| Ubiquitin and ubiquitin?modified proteins activate the Pseudomonas aeruginosa T3SS cytotoxin, ExoU
DM Anderson, KM Schmalzer, H Sato, M Casey, SS Terhune, AL Haas, …
Molecular microbiology 82 (6), 1454-1467
|
32 | 2011 |
| Effect of regB on expression from the P1 and P2 promoters of the Pseudomonas aeruginosa regAB operon.
DG Storey, TL Raivio, DW Frank, MJ Wick, S Kaye, BH Iglewski
Journal of bacteriology 173 (19), 6088-6094
|
32 | 1991 |
| Characterization of a gene that regulates toxin A synthesis in Pseudomonas aeruginosa
MS Hindahl, DW Frank, A Hamood, BH Iglewski
Nucleic acids research 16 (12), 5699-5699
|
32 | 1988 |
| Multi-functional characteristics of the Pseudomonas aeruginosa type III needle-tip protein, PcrV; comparison to orthologs in other Gram-negative bacteria
H Sato, DW Frank
Frontiers in microbiology 2
|
31 | 2011 |
| Isolation and characterization of monoclonal antibodies to Bordetella pertussis
DW Frank, CD Parker
Journal of biological standardization 12 (4), 353-365
|
31 | 1984 |
| Functional analysis of exsC and exsB in regulation of exoenzyme S production by Pseudomonas aeruginosa.
J Goranson, AK Hovey, DW Frank
Journal of bacteriology 179 (5), 1646-1654
|
29 | 1997 |
| Children with cystic fibrosis produce an immune response against exoenzyme S, a type III cytotoxin of Pseudomonas aeruginosa
B Banwart, ML Splaingard, PM Farrell, MJ Rock, PL Havens, J Moss, …
Journal of Infectious Diseases 185 (2), 269-270
|
28 | 2002 |
| Genetics and genetic manipulation in Francisella tularensis
DW Frank, TC Zahrt
Annals of the New York Academy of Sciences 1105 (1), 67-97
|
27 | 2007 |
| Genetic analysis of exoenzyme S expression by Pseudomonas aeruginosa
J Goranson, DW Frank
FEMS microbiology letters 135 (2-3), 149-155
|
24 | 1996 |
| Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activity
SL Sayner, R Balczon, DW Frank, DMF Cooper, T Stevens
American Journal of Physiology-Lung Cellular and Molecular Physiology 301 (1 …
|
19 | 2011 |
| ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation
U Beckert, S Wolter, C Hartwig, H Bähre, V Kaever, D Ladant, DW Frank, …
Biochemical and biophysical research communications 450 (1), 870-874
|
17 | 2014 |
| Five mechanisms of manipulation by bacterial effectors: a ubiquitous theme
DM Anderson, DW Frank
PLoS Pathog 8 (8), e1002823
|
16 | 2012 |
| The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury
TC Stevens, CD Ochoa, KA Morrow, MJ Robson, N Prasain, C Zhou, …
American Journal of Physiology-Lung Cellular and Molecular Physiology 306 …
|
15 | 2014 |
| Activation of ExoU phospholipase activity requires specific C-terminal regions
KM Schmalzer, MA Benson, DW Frank
Journal of bacteriology 192 (7), 1801-1812
|
15 | 2010 |
| Modified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosa
H Sato, ML Hunt, JJ Weiner, AT Hansen, DW Frank
PLoS One 6 (3), e18356
|
14 | 2011 |
| Identification of the major ubiquitin-binding domain of the Pseudomonas aeruginosa ExoU A2 phospholipase
DM Anderson, JB Feix, AL Monroe, FC Peterson, BF Volkman, AL Haas, …
Journal of Biological Chemistry 288 (37), 26741-26752
|
13 | 2013 |
| Mechanisms of lung epithelial cell injury by Pseudomonas aeruginosa
JP Wiener-Kronish, D Frank, T Sawa
Molecular biology of acute lung injury, 149-161
|
13 | 2001 |
| Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection
JT Barbieri, DW Frank, SM Kulich
US Patent 5,599,665
|
12 | 1997 |
| A sensitive fluorescence-based assay for the detection of ExoU-mediated PLA 2 activity
MA Benson, KM Schmalzer, DW Frank
Clinica Chimica Acta 411 (3), 190-197
|
11 | 2010 |
| cCMP and cUMP occur in vivo
H Bähre, C Hartwig, A Munder, S Wolter, T Stelzer, B Schirmer, U Beckert, …
Biochemical and biophysical research communications 460 (4), 909-914
|
9 | 2015 |
| Isolation and characterization of an attenuated strain of Pseudomonas aeruginosa AC869, a 3, 5-dichlorobenzoate degrader.
X Zhou, SE George, DW Frank, M Utley, I Gilmour, KA Krogfelt, …
Applied and environmental microbiology 63 (4), 1389-1395
|
9 | 1997 |
| Pseudomonas aeruginosa exotoxin Y-mediated tau hyperphosphorylation impairs microtubule assembly in pulmonary microvascular endothelial cells
R Balczon, N Prasain, C Ochoa, J Prater, B Zhu, M Alexeyev, S Sayner, …
PloS one 8 (9), e74343
|
7 | 2013 |
| Intoxication of Host Cells by the T3SS Phospholipase ExoU: PI (4, 5) P 2-Associated, Cytoskeletal Collapse and Late Phase Membrane Blebbing
H Sato, DW Frank
PloS one 9 (7), e103127
|
6 | 2014 |
| Research topic on Pseudomonas aeruginosa, biology, genetics, and host–pathogen interactions
DW Frank
Pseudomonas Aeruginosa, Biology, Genetics, and Host-pathogen Interactions, 4
|
6 | 2012 |
| Induced conformational changes in the activation of the Pseudomonas aeruginosa type III toxin, ExoU
MA Benson, SM Komas, KM Schmalzer, MS Casey, DW Frank, JB Feix
Biophysical journal 100 (5), 1335-1343
|
6 | 2011 |
| Genetic studies of Pseudomonas aeruginosa toxin A.
DW Frank, SF Steinbach, JM Bradley, BH Iglewski
ZENTRALBL. BAKTERIOL. MIKROBIOL. HYG. 1986.
|
5 | 1986 |
| Surface antigens of Bordetella pertussis
CD Parker, SK Armstrong, DW Frank
Immunobiology of Proteins and Peptides—III, 117-127
|
5 | 1985 |
| In the absence of effector proteins, the Pseudomonas aeruginosa type three secretion system needle tip complex contributes to lung injury and systemic inflammatory responses
JP Audia, AS Lindsey, NA Housley, CR Ochoa, C Zhou, M Toba, M Oka, …
PloS one 8 (11), e81792
|
4 | 2013 |
| Pseudomonas aeruginosa exoenzyme S, a bifunctional cytotoxin secreted by a type-III pathway
JT Barbieri, DW Frank
Bacterial Protein Toxins, 235-251
|
4 | 2000 |
| [40] Regulation of expression of Pseudomonas exotoxin a by iron
DW Frank, DG Storey
Methods in enzymology 235, 502-517
|
4 | 1994 |
| Control of bacterial soft rot caused by Pseudomonas cattleya in the culture of Phalaenopsis
DW Frank
The Orchid digest (USA)
|
4 | 1988 |
| Cell surface antigens of Bordetella pertussis.
CD Parker, LV Branes, SK Armstrong, DW Frank, A Cole
Developments in biological standardization 61, 123-136
|
4 | 1984 |
| Ubiquitin activates patatin-like phospholipases from multiple bacterial species
DM Anderson, H Sato, AT Dirck, JB Feix, DW Frank
Journal of bacteriology 197 (3), 529-541
|
3 | 2015 |
| Method and compositions for immunization with the Pseudomonas V antigen
DW Frank, J Wiener-Kronish, TL Yahr, T Sawa, RB Fritz
US Patent 8,101,347
|
2 | 2012 |
| ExoY increases Pseudomonas aeruginosa virulence
N Prasain, DF Alvarez, DW Frank, T Stevens
The FASEB Journal 22 (1_MeetingAbstracts), 928.6
|
2 | 2008 |
| Pseudomonas aeruginosa toxins
AW Maresso, DW Frank, JT Barbieri
The Comprehensive Sourcebook of Bacterial Protein Toxins, 257
|
2 | 2005 |
| Method of and compositions for immunization with the pseudomonas V antigen
DW Frank, J Wiener-Kronish, TL Yahr, T Sawa, RB Fritz
US Patent 6,827,935
|
2 | 2004 |
| Humanized anti-PerV monoclonal antibody IM166 binds to the type III toxin delivery system of Pseudomonas aeruginosa and prevents mortality in an animal model of Pseudomonas-induced pneumonia.
EG Spack, T Sawa, J Wiener-Kronish, DW Frank, W Emlen
FASEB JOURNAL 16 (4), A311-A311
|
2 | 2002 |
| Evidence that all Pseudomonas aeruginosa strains may be inherently capable of invading corneal epithelial cells and that cytotoxicity is regulated by EXSA.
SMJ Fleiszig, JP WienerKronish, V Vallas, KE Mostov, DW Frank
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37 (3), 965-965
|
2 | 1996 |
| Heterogeneity of pulmonary endothelial cyclic nucleotide response to Pseudomonas aeruginosa ExoY infection
KA Morrow, R Seifert, V Kaever, AL Britain, SL Sayner, CD Ochoa, …
American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …
|
1 | 2015 |
| Cross Kingdom Activators of Five Classes of Bacterial Effectors
DM Anderson, JB Feix, DW Frank
PLoS Pathog 11 (7), e1004944
|
1 | 2015 |
| Reproducible and Quantitative Model of Infection of Dermacentor variabilis with the Live Vaccine Strain of Francisella tularensis
J Coburn, T Maier, M Casey, L Padmore, H Sato, DW Frank
Applied and environmental microbiology 81 (1), 386-395
|
1 | 2015 |
| In vitro Assays to Monitor the Activity of Pseudomonas aeruginosa Type III Secreted Proteins
SL Rolsma, DW Frank
Pseudomonas Methods and Protocols, 171-184
|
1 | 2014 |
| Pseudomonas aeruginosa ExoY, a cyclic GMP-and cyclic UMP-generating nucleotidyl cyclase
R Seifert, C Hartwig, S Wolter, D Reinecke, H Burhenne, V Kaever, …
BMC Pharmacology and Toxicology 14 (Suppl 1), O36
|
1 | 2013 |
| Targets Of Subplasma Membrane Versus Cytosolic Adenylyl Cyclase Activity Demonstrate The Bidirectional Nature Of The CAMP Diffusion Barricade That Maintains Pulmonary Endothelial Barrier Integrity
R Balczon, D Frank, D Cooper, T Stevens, S Sayner
Am J Respir Crit Care Med 181, A1037
|
1 | 2010 |
| Type III secretory proteins in Pseudomonas aeruginosa
H Sato, DW Frank
Virulence Mechanisms of Bacterial Pathogens
|
1 | 2007 |
| AraC Family Regulators and Transcriptional Control of Bacterial Virulence Determinants
DW Frank, ML Hunt
American Society of Microbiology
|
1 | 2003 |
| Rapid IL-10 upregulation in lung in cytotoxic Pseudomonas aeruginosa pneumonia
T Sawa, M Ohara, K Kurahashi, MA Gropper, DW Frank, …
FASEB JOURNAL 12 (5), A1071-A1071
|
1 | 1998 |
| Pseudomonas aeruginosa inhibits Fc receptor-mediated phagocytosis.
M Ohara, T Sawa, K Kurahashi, TL Yahr, DW Frank, JP Wiener-Kronish, …
JOURNAL OF INVESTIGATIVE MEDICINE 46 (3), 218A-218A
|
1 | 1998 |
| Pathogenesis of acute lung injury caused by Pseudomonas aeruginosa-Major contribution of type III secretory system.
T Sawa, M Ohara, K Kurahashi, TL Yahr, MA Gropper, DW Frank, …
JOURNAL OF INVESTIGATIVE MEDICINE 46 (3), 225A-225A
|
1 | 1998 |
| ASSOCIATION OF PSEUDOMONAS-AERUGINOSA CYTOTOXICITY WITH THE PRODUCTION OF EXOENZYME-S
JP WIENERKRONISH, G Apodaca, DW FRANK, K Mostov
FASEB JOURNAL 7 (4), A675-A675
|
1 | 1993 |
| Art-shade phalaenopsis.
M Rose, HP Norton, J Martin, CF Fighetti, DW Frank
American Orchid Society bulletin
|
1 | 1993 |
| Yellow Phalaenopsis
CF Fighetti, DW Frank, J Martin, HP Norton, M Rose
American Orchid Society bulletin (USA)
|
1 | 1993 |
| EXOENZYME-S SECRETED BY PSEUDOMONAS-AERUGINOSA CAUSES ALVEOLAR EPITHELIAL DAMAGE IN A RABBIT MODEL OF PNEUMONIA
I Kudoh, JF Pittet, D Frank, T Sakuma, MA Matthay, J WIENERKRONISH
FASEB JOURNAL 6 (4), A1535-A1535
|
1 | 1992 |
| Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathy
KA Morrow, CD Ochoa, R Balczon, C Zhou, L Cauthen, M Alexeyev, …
American Journal of Physiology-Lung Cellular and Molecular Physiology …
|
2015 | |
| Pseudomonas aeruginosa toxins
S Rolsma, DW Frank, JT Barbieri
The Comprehensive Sourcebook of Bacterial Protein Toxins, 133
|
2015 | |
| Pseudomonas aeruginosa Exoenzymes U and Y Induce a Transmissible Endothelial Tauopathy
K Morrow, C Ochoa, R Balczon, L Cauthen, M Alexeyev, K Schmalzer, …
The FASEB Journal 29 (1 Supplement), 661.5
|
2015 | |
| Heterogeneity of Pulmonary Endothelial Cyclic Nucleotide Response to Pseudomonas aeruginosa Infection
K Morrow, R Seifert, A Britain, C Ochoa, E Cioffi, D Frank, T Rich, …
The FASEB Journal 29 (1 Supplement), 661.6
|
2015 | |
| The effector protein ExoY secreted by Pseudomonas aeruginosa augments the inflammatory reaction in the respiratory tract of mice
J Rothschuh, A Munder, B Tuemmler, D Frank, R Seifert, C Hartwig
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 388, S27-S27
|
2015 | |
| cCMP and cUMP occur in vivo
B Schirmer, U Beckert, DW Frank, B Tümmler, V Kaever, R Seifert
Biochemical and Biophysical Research Communications 30, 1e6
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2015 | |
| Pseudomonas aeruginosa induces the production and release of a cytotoxic factor from pulmonary endothelial cells
RD Balczon, A Morrow, B Edmonds, L Cauthen, D Frank, T Stevens
MOLECULAR BIOLOGY OF THE CELL 25
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2014 | |
| Pseudomonas aeruginosa infection causes endothelial cell Tau aggregation: evidence for an endothelial tauopathy (1176.5)
K Morrow, C Ochoa, M Alexeyev, D Frank, R Balczon, T Stevens
The FASEB Journal 28 (1 Supplement), 1176.5
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2014 | |
| ExoY from Pseudomonas aeruginosa, a preferential guanylyl and uridylyl cyclase (610.2)
R Seifert, U Beckert, D Frank
The FASEB Journal 28 (1 Supplement), 610.2
|
2014 | |
| Feel the Burn, then Feel the Death. ExoU as a Phospholipase
E Bord, Z Farrell, W Heur, W Keslin, R Laughlin, H Leedom, A LeMense, …
The FASEB Journal 27 (1_MeetingAbstracts), lb180
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2013 | |
| The Pseudomonas AerugINOSa Exotoxin Y Induces Aggregated Endothelial Tau Release As A Putative Mechanism Of Cell Growth Suppression And Impaired Angiogenesis
TC Stevens, CD Ochoa, DW Frank, R Balczon, T Stevens, KA Morrow
Am J Respir Crit Care Med 187, A5921
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2013 | |
| The Pseudomonas AerugINOSa Exotoxin Y Impairs Endothelial Cell Proliferation, Angiogenesis, And Vascular Repair Following Lung Injury
CD Ochoa, MJ Robson, C Zhou, KA Morrow, DF Alvarez, D Frank, …
Am J Respir Crit Care Med 187, A5916
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2013 | |
| Pseudomonas AerugINOSa Decreases Merlin Phosphorylation In Pulmonary Endothelium As A Mechanism Of Growth Suppression
DW Frank, LA Shevde, T Stevens, KA Morrow
Am J Respir Crit Care Med 187, A3706
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2013 | |
| The Pseudomonas Aeruginosa Exotoxin U Causes Endothelial Cell Tau Aggregation: Evidence For A Tauopathy Of The Lung
CD Ochoa, M Alexeyev, DW Frank, JP Audia, R Balczon, T Stevens, …
Am J Respir Crit Care Med 187, A3715
|
2013 | |
| Treating bacterial virulence systems: we are not there yet
YJ Huang, EA Bittner, D Frank, J Wiener-Kronish
Intensive care medicine, 1-2
|
2012 | |
| The Pseudomonas AerugINOSa Exotoxin Y Induces Inter-Endothelial Cell Gaps And Impairs Migration And Proliferation
CD Ochoa, DW Frank, MJ Robson, T Stevens, TC Stevens
Am J Respir Crit Care Med 185, A3666
|
2012 | |
| Pseudomonas AerugINOSa Impairs The Activation Of Store Operated Calcium Entry Via Microtubule-Associated Protein 6
CD Ochoa, TC Stevens, M Alexeyev, DW Frank, T Stevens, MJ Robson
Am J Respir Crit Care Med 185, A5505
|
2012 | |
| The effector protein ExoY secreted by Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for GTP
U Voigt, H Burhenne, L Sonnow, C Wölfel, C Spangler, D Ladant, …
BMC Pharmacology 11 (Suppl 1), P74
|
2011 | |
| Infection of epithelial cells with Pseudomonas aeruginosa produces high concentrations of cCMP, cGMP and cUMP
U Voigt, DW Frank, V Kaever, R Seifert
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 383, 16-16
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2011 | |
| Pseudomonas aeruginosa toxin ExoY-biochemical characterization of a nucleotidyl cyclase
L Sonnow, DW Frank, V Keever, J von der Ohe, R Seifert
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 383, 25-25
|
2011 | |
| The Pseudomonas Aeruginosa Exotoxin Y Impairs Microtubule Assembly In Pulmonary Microvascular Endothelial Eells
N Prasain, J Prater, M Alexeyev, B Zhu, S Sayner, D Frank, T Stevens, …
Am J Respir Crit Care Med 183, A4180
|
2011 | |
| Pseudomonas Aeruginosa Exotoxin Y Increases Intracellular Levels Of Both CAMP And CGMP In Pulmonary Microvascular Endothelial Cells
M Alexeyev, D Frank, T Stevens, C Ochoa
Am J Respir Crit Care Med 183, A4179
|
2011 | |
| Pseudomonas aeruginosa toxin ExoY, a cUMP/cGMP-producing nucleotidyl cyclase
C Wölfel, DW Frank, S Wolter, V Kaever, R Seifert
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 381, 29-29
|
2010 | |
| P. aeruginosa ExoY Increases Lung Endothelial Permeability with a Concomitant Decrease in Lung Vascular Compliance
N Prasain, DF Alvarez, DW Frank, T Stevens
The FASEB Journal 23 (1_MeetingAbstracts), 1024.11
|
2009 | |
| Type III secretory proteins in Pseudomonas aeruginosa.
H Sato, DW Frank, KA Brogden, FC Minion, N Cornick, TB Stanton, …
Virulence mechanisms of bacterial pathogens, 3-22
|
2006 | |
| P-aeruginosa adenylyl cyclase (ExoY) increases cAMP causing intercellular gap formation in pulmonary microvascular endothelium
S Sayner, D Frank, J VandeWaa, T Stevens
FASEB JOURNAL 17 (4), A412-A412
|
2003 | |
| Functional association of endogenous adenylyl cyclases and phosphodiesterases in pulmonary microvascular endothelial cells revealed by P-aeruginosa adenylyl cyclase, ExoY
S Sayner, D Frank, J VandeWaa, T Stevens
FASEB JOURNAL 17 (4), A412-A412
|
2003 | |
| A method of inhibiting, moderating or diagnosing pseudomonas aeruginosa infection is disclosed.
DW Frank, TL Yahr, T Sawa, J Wiener-Kronish
US Patent 6,309,651
|
2001 | |
| Association of mortality with type III secretory protein phenotype in lower respiratory tract and systemic Pseudomonas aeruginosa infections
A Roy-Burman, RH Savel, S Racine, J Fujimoto, NS Revadigar, T Sawa, …
CRITICAL CARE MEDICINE 28 (12), A193-A193
|
2000 | |
| Resistance of strains of Pseudomonas aeruginosa to contact lens disinfectants.
C Lakkis, DW Frank, AS Bruce, SMJ Fleiszig
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38 (4), 2415-2415
|
1997 | |
| Pseudomonas aeruginosa induced cytotoxicity for corneal epithelium: Cell invasion is not a prerequisite.
SMJ Fleiszig, DJ Evans, V Vallas, DW Frank
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38 (4), 5334-5334
|
1997 | |
| Pseudomonas aeruginosa nucleic acids encoding exoenzyme S activity and use thereof in detecting pseudomonas aeruginosa infection
JT Barbieri, DW Frank, SM Kulich
Biotechnology Advances 15 (3), 723-723
|
1997 | |
| Red Phalaenopsis hybrids
J Martin, HP Norton, M Rose, CF Fighetti, DW Frank
American Orchid Society bulletin (USA)
|
1993 | |
| Molecular Studies of Pseudomonas aeruginasa Exotoxin A
DW FRANK, E SUSAN, H Wesr
Molecular Basis of Bacterial Pathogenesis, 427
|
1990 | |
| The Role of Exoenzyme S in Pseudomonas aeruginosa Infections
BH Inglewski, DW Frank, S Steinbach, TI Nicas, JH Crosa
OREGON HEALTH SCIENCES UNIV PORTLAND
|
1988 | |
| 171 TATG ACT GCG ACA GAC AGA ACG CCC CCG CC ATTG
MS Hindahl, DW Frank, A Hamood, BH Iglewski
Nucleic Acids Research 16, 5699
|
1988 | |
| The Pseudomonas Aeruginosa Type Three Secretion System Inhibits Store Operated Calcium Entry
TC Stevens, C Ochoa, D Frank, T Stevens, M Robson
Am J Respir Crit Care Med 183, 2011
|
1944 | |
| The Pseudomonas Aeruginosa Exotoxin Y Impairs Endothelial Cell Mobility
M Robson, C Ochoa, D Frank, T Stevens, TC Stevens
Am J Respir Crit Care Med 183, 2011
|
1943 | |
| Pseudomonas AerugINOSa Exotoxin Promotes Microtubule-Associated Protein 6 Binding To Pulmonary Microvascular Endothelial Cell Microtubules
MJ Robson, TC Stevens, R Balczon, DW Frank, T Stevens, CD Ochoa
Am J Respir Crit Care Med 185, 2012
|
1862 | |
| Volume 61 January 1993
SAB Jaynes, JC Newton, FM Enright, TG Snider III, RJ Mehigh, R Robert, …
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| Francisella tularensis Mutagenesis of
C Zahrt, DW Frank
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